Prolia is a prescription medicine used to treat symptoms of osteoporosis and to increase bone mass in patients receiving certain types of cancer. Prolia may be used alone or with other medications.

Prolia belongs to a class of drugs called Antineoplastics, Monoclonal Antibody; Monoclonal Antibodies, Endocrine.

Prolia (denosumab) is a human IgG2 monoclonal antibody with affinity and specificity for human RANKL (receptor activator of nuclear factor kappa-B ligand). Denosumab has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells.

Prolia Info

The recommended dose of Prolia is 60 mg administered as a single subcutaneous injection once every 6 months. Administer Prolia via subcutaneous injection in the upper arm, the upper thigh, or the abdomen. All patients should receive calcium 1000 mg daily and at least 400 IU vitamin D daily [see WARNINGS AND PRECAUTIONS].

If a dose of Prolia is missed, administer the injection as soon as the patient is available. Thereafter, schedule injections every 6 months from the date of the last injection.

Prolia Side Effects

The most common side effects include: 

  • bladder infection,
  • painful or difficult urination,
  • back pain,
  • muscle pain, and
  • pain in your arms or legs



Patient Assistance Programs

There are several programs patients can sign up for that will assist in treatment costs: 


To learn more about Prolia, browse the resources below.

Order Form

Ready to get started?

Contact us to chat with one of our helpful scheduling specialists!