Simponi Aria is a prescription medicine used to treat the symptoms of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing, and Ulcerative Colitis. Simponi Aria may be used alone or with other medications.

Simponi Aria belongs to a class of drugs called Antipsoriatics, Systemic; DMARDs, TNF Inhibitors; Monoclonal Antibodies; Inflammatory Bowel Disease.

Golimumab is a human IgG1κ monoclonal antibody specific for human tumor necrosis factor-alpha (TNFα) that exhibits multiple glycoforms with molecular masses of approximately 150 to 151 kilodaltons. Golimumab was created using genetically engineered mice immunized with human TNF, resulting in an antibody with human-derived antibody variable and constant regions. Golimumab is produced by a recombinant cell line cultured by continuous perfusion and is purified by a series of steps that includes measures to inactivate and remove viruses.